The association of physical activity before and after lymphoma diagnosis with survival outcomes

摘要: The impact of physical activity (PA) on lymphoma survival is not known. association PA and change in with overall (OS), lymphoma-specific (LSS) event-free (EFS) was evaluated a prospective cohort newly diagnosed patients (2002-2012). We calculated Leisure Score Indexes (mLSI) from the self-reported usual adult (baseline) at 3-years post-diagnosis (FU3), grouping by active vs insufficiently American Cancer Society guidelines. Associations were assessed using hazard ratios (HRs) 95% confidence intervals (CI) Cox models stratified subtype, adjusted for age, sex, baseline BMI, comorbidity score scores further PA. Three thousand sixty participants evaluable 1371 FU3. Active had superior [HR (CI): OS 0.82 (0.72-0.94); LSS 0.74 (0.61-0.90); EFS 0.92 (0.82-1.02)] FU3 0.64 (0.46-0.88); 0.32 (0.18-0.59); (0.61-1.10)] compared to active. An increase mLSI (vs stable mLSI) associated (HR = 0.70, CI 0.49-1.00) 0.49, 0.26-0.94).The continuous significantly OS, EFS; maintained across subgroups appeared linear. Higher among diagnosis 3 years LSS, EFS. Increasing after improved supporting an important role survivorship need intervention trials.