Multiple parallelisms in animal cytokinesis.

摘要: The process of cytokinesis in animal cells is usually presented as a relatively simple picture: A cleavage plane first positioned the equatorial region by astral microtubules anaphase mitotic apparatus, and contractile ring made up parallel filaments actin myosin II formed encircles cortex at division site. Active sliding between two filament systems constricts perimeter cortex, leading to separation daughter cells. However, recent studies both lower eukaryotic model organisms have demonstrated that actually far more complex. It now obvious three key processes cytokinesis, determination, furrowing, scission, are driven different mechanisms types In some cases, moreover, multiple pathways appear redundant functions single cell type. this review, we present novel hypothesis incorporates observations on activities biochemistry Rho-type GTPase proteins postulates sets responsible for known determination also distinct furrowing.