Convenient Synthesis of a New Series of 3-Triazolonyl Iminocoumarins

作者: Myriam Kammoun , Hamida Turki , Suzanne Fery-Forgues , Rachid El Gharbi

DOI: 10.1080/00397910903026681

关键词:

摘要: 3-Cyano-7-diethylamino-N-ethoxycarbonyl-iminocoumarin reacted with different hydrazines as N-nucleophiles to afford, in one step, a new series of 2-N-substituted 3-triazolonyl-iminocoumarins good yields. In two cases, N-unsubstituted derivatives were also obtained. The structures all the products obtained confirmed by infrared, 1H NMR, 13C and elemental analysis. optical properties three these compounds dichloromethane ethanol reported.

参考文章(38)
Bentley Ew, A review of anticoagulant rodenticides in current use. Bulletin of The World Health Organization. ,vol. 47, pp. 275- 280 ,(1972)
S. Sardari, S. Nishibe, M. Daneshtalab, Coumarins, the bioactive structures with antifungal property Studies in natural products chemistry. ,vol. 23, pp. 335- 393 ,(2000) , 10.1016/S1572-5995(00)80133-7
Mehdi Fakhfakh, Hamida Turki, Souhir Abid, Rachid El Gharbi, Suzanne Fery-Forgues, Preparation and optical properties of new fluorescent iminocoumarins: Study of N-acyl-derivatives Journal of Photochemistry and Photobiology A-chemistry. ,vol. 185, pp. 13- 18 ,(2007) , 10.1016/J.JPHOTOCHEM.2006.04.036
Hamida Turki, Souhir Abid, Suzanne Fery-Forgues, Rachid El Gharbi, Optical properties of new fluorescent iminocoumarins: Part 1 Dyes and Pigments. ,vol. 73, pp. 311- 316 ,(2007) , 10.1016/J.DYEPIG.2006.01.001
Veeresh Maddi, Kallur S. Raghu, M.N.A. Rao, Synthesis and Anti-Inflammatory Activity of 3-(Benzylideneamino)Coumarins in Rodents Journal of Pharmaceutical Sciences. ,vol. 81, pp. 964- 966 ,(1992) , 10.1002/JPS.2600810926
H. Turki, S. Abid, Y. Le Bigot, S. Fery‐Forgues, R. El Gharbi, Novel Synthesis of 2‐Oxo‐2H‐Benzopyrano[2,3‐d]Pyrimidines Synthetic Communications. ,vol. 34, pp. 3553- 3563 ,(2004) , 10.1081/SCC-200031013
Denise Egan, Richard O'kennedy, Elizabeth Moran, Dermot Cox, Ena Prosser, R. Douglas Thornes, The Pharmacology, Metabolism, Analysis, and Applications of Coumarin and Coumarin-Related Compounds Drug Metabolism Reviews. ,vol. 22, pp. 503- 529 ,(1990) , 10.3109/03602539008991449
O. V. Khilya, O. V. Shablykina, M. S. Frasinyuk, V. V. Ishchenko, V. P. Khilya, 3-(2-Pyridyl)coumarins Chemistry of Natural Compounds. ,vol. 41, pp. 523- 528 ,(2005) , 10.1007/S10600-005-0197-5
Conor N. O'Callaghan, T. Brain H. McMurry, John E. O'Brien, Sylvia M. Draper, Deborah J. Wilcock, Formation of polyheterocyclic systems by reaction of 2-imino-4-methyl-2H-1-benzopyran-3-carbonitrile with active methylene compounds Journal of The Chemical Society-perkin Transactions 1. pp. 1067- 1071 ,(1996) , 10.1039/P19960001067
J.R.S. Hoult, Miguel Payá, Pharmacological and biochemical actions of simple coumarins : Natural products with therapeutic potential General Pharmacology-the Vascular System. ,vol. 27, pp. 713- 722 ,(1996) , 10.1016/0306-3623(95)02112-4