The Burden of Disease in Rheumatoid Arthritis

摘要: Rheumatoid arthritis (RA) is a chronic inflammatory disease which, if left untreated, leads to functional disability, pain, reduced health-related quality of life and premature mortality. Between 0.5% 1% the population are affected worldwide, between 25 50 new cases evolve in 100,000. Practically all patients with RA require initiation disease-modifying antirheumatic treatment retard or stop progression, control manifestations reduce burden. If course monitored adjustment medication, lifestyle factors, exercise, as well physical activity levels, co-morbidities may be prevented RA. During last decade, major progress has been made treating through early identification disease. Many still experience work disability co-morbidities. For societies, economic burden high terms direct indirect costs, including modern drug treatment.