作者: Maurizio Pesce , Giulio Pompilio , Maurizio C. Capogrossi
DOI: 10.1007/978-1-84882-718-9_21
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摘要: The use of Endothelial Progenitor Cells (EPCs) in therapy is nowadays considered a feasible option to enhance neo-vascularization the ischemic heart and lower limbs. Although autologous EPC sources such as bone marrow (BM) peripheral blood (PB) have been already validated for their promote angiogenesis, heterologous cord (CB) not yet approved patients, due risk immune response induction. Studies animal models ischemia shown, however, that protocols pharmacologically suppress allow potentially successful cord-blood-derived CD34+ cells.