Metabolism of 2′,2′-Difluoro-2′-Deoxycytidine and Radiation Sensitization of Human Colon Carcinoma Cells

作者: Larry W. Hertel , Theodore S. Lawrence , Emily Chang , Donna S. Shewach , Tina M. Hahn

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摘要: Difluorodeoxycytidine (dFdCyd) is a new antimetabolite with clinical activity in patients with solid tumors but not leukemias. We have studied the metabolism, cytotoxicity, and …

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