Diarrhea Due to Escherichia coli in the Rabbit: A Novel Mechanism
作者： J. R. Cantey , R. K. Blake
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摘要: A strain of Escherichia coli O15 (RDEC-1) isolated from several rabbits with diarrhea was examined to determine (1) whether the could produce when administered by orogastric route other and (2) this invasive or enterotoxigenic. Strain RDEC-1 produced in 48 62 given doses that ranged 1.5 X 10(2) 4 10(10) bacteria. The organism did not give a positive result 18-hr ileal loop Sereny tests invade HeLa cells. Culture supernatants results 6- rabbit loop, suckling mouse, Y-1 adrenal cell, Chinese hamster ovary cell assays. Fluorescent antibody staining sections intestine prepared cryostat revealed great numbers E. adhered epithelial surface. It is evident can without being able mucosa synthesize enterotoxin. Strains similar may account for some coli-associated occurs humans.
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