Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor

作者: Philip R. Kym , Mathew M. Mulhern , Andrew S. Judd , Ju Gao , Christine A. Collins

DOI:

关键词:

摘要: The present invention relates to the antagonism of effects melanin-concentrating hormone (MCH) through melanin concentrating receptor which is useful for prevention or treatment eating disorders, weight gain, obesity, abnormalities in reproduction and sexual behavior, thyroid secretion, diuresis water/electrolyte homeostasis, sensory processing, memory, sleeping, arousal, anxiety, depression, seizures, neurodegeneration psychiatric disorders.

参考文章(25)
Raffaello Masciadri, Werner Hofheinz, Quinoline derivatives for treating malaria ,(1996)
Kyoichi Maeno, Shin-Ichi Tsukamoto, Itsuro Shimada, Hideki Kubota, Shuichi Sakamoto, Fumikazu Wanibuchi, 5-HT2c RECEPTOR AGONISTS AND AMINOALKYLINDAZOLE DERIVATIVES ,(1998)
Bertram Schwartz, Richard C. Miller, Optical monitoring photodiode system ,(1978)
Michael Wurl, Rainer Walenta, Ulf Preuschoff, Reiner Muller-Peddinghaus, Ivan Ban, 3-flavone carboxylic acid compounds ,(1989)
Nicholas Kindor, Richard Evans, Stephen Thom, Brian Springthorpe, David Harden, David Marriott, Matthew Perry, Andrew Baxter, Thomas McInally, Substituted piperidine compounds useful as modulators of chemokine receptor activity ,(2000)
Jurgen Rockle, Thomas Blumke, Optoelectrical sending and receiving apparatus ,(1990)
Roger M. Freidinger, Douglas J. Pettibone, Doug W. Hobbs, Ben E. Evans, Peter D. Williams, Paul S. Anderson, Mark G. Bock, Benzoxazinone and benzopyrimidinone piperidinyl tocolytic oxytocin receptor antagonists ,(1994)
Lothar Schwink, Siegfried Stengelin, Gerard Rosse, Armin Walser, Matthias Gossel, Aminoalkyl-substituted aromatic bicyclic compounds, method for the production thereof and their use as medicaments ,(2002)