A practical asymmetric synthesis of (R)-fluoxetine and its major metabolite (R)-norfluoxetine
作者： James W Hilborn , Zhi-Hui Lu , Alex R Jurgens , Q.Kevin Fang , Paul Byers
DOI: 10.1016/S0040-4039(01)01877-9
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摘要: A convenient and chromatography-free synthesis for the enantiomers of fluoxetine and norfluoxetine is described. The synthesis relied on the use of the CBS reduction, and Hofman …
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