Do Women with Diabetes Need More Intensive Action for Cardiovascular Reduction than Men with Diabetes

摘要: This narrative review makes the case for greater efforts to reduce cardiovascular disease (CVD) risk in women with diabetes. In a recent meta-analysis including five CVOTs of diabetes medications 46,606 subjects, (vs men) type 2 had higher relative stroke (RR 1.28; 95% CI 1.09, 1.50) and heart failure (1.30; 1.21, 1.40). Prior studies found “within-gender” RR CVD mortality although men have an absolute risk. Women prior gestational mellitus (GDM) 2-fold than background population. Worse factor management women, as well lower female therapy adherence, contribute further these disparities. The mechanism behind this excess includes biological, hormonal, socioeconomic, clinical, behavioral factors that still require investigation. need more intensive reduction now attention screening both incident among high-risk women.