The triplex vaccine effects in mammary carcinoma: A nonlinear model in tune with SimTriplex ☆
作者： Carlo Bianca , Marzio Pennisi
DOI: 10.1016/J.NONRWA.2011.12.019
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摘要: Abstract This paper deals with the mathematical modeling of mammary carcinoma–immune system competition elicited by an external stimulus represented three different protocols triplex vaccine [C. De Giovanni, et al., Immunoprevention HER-2/neu transgenic carcinoma through interleukin 12-engineered allogeneic cell vaccine, Cancer Research 64 (2004) 4001–4009]. The presented model is composed nonlinear ordinary differential equations based on parameters and populations. A qualitative analysis asymptotic behavior numerical simulations are able to depict preclinical experiments mice in tune SimTriplex [F. Pappalardo, F. Castiglione, P.L. Lollini, S. Motta, Modelling simulation cancer immunoprevention Bioinformatics 21 (2005) 2891–2897]. results great interest both applied theoretical sciences.
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