作者: Christoph H. Saely , Heinz Drexel
DOI: 10.1007/S10354-010-0745-X
关键词:
摘要: LDL cholesterol plays a central role in atherogenesis and lowering statin therapy significantly reduces cardiovascular risk patients with diabetes. Therefore, current guidelines is the primary target of lipid intervention. All type 2 diabetes should reach an <100 mg/dl, very-high both coronary artery disease <70 mg/dl. Given overwhelming body evidence for efficacy respect to event prevention, primarily be lowered by statins. Many will require high-dose meet stringent treatment goal Importantly, typically exhibit pattern dyslipidemia high triglycerides, low HDL cholesterol, small, atherogenic particles, which strong predictor vascular events Despite currently limited from large clinical endpoint-trials additional this diabetic niacin or fibrates therefore appears promising option at least combination disease.