Saruplase in Myocardial Infarction.

作者: Hannes Barth , Gwyn Hopkins , Jurgen Meyer , Wolfgang A. Grünzier , Jean Boland

DOI: 10.1007/BF01062710

关键词:

摘要: Saruplase is an unglucosylated single-chain recombinant urokinase-type plasminogen activator. Dose finding studies in patients with acute myocardial infarction indicated that a dose of 80 mg saruplase, given as bolus 20 and iv infusion 60 one hour, led to excellent patency figures.

参考文章(35)
The thrombolysis in myocardial infarction (TIMI) trial. The New England Journal of Medicine. ,vol. 313, pp. 1018- ,(1985) , 10.1056/NEJM198510173131611
GRUPPOITALIANOPERLOSTUDIODELL, EFFECTIVENESS OF INTRAVENOUS THROMBOLYTIC TREATMENT IN ACUTE MYOCARDIAL INFARCTION The Lancet. ,vol. 327, pp. 397- 402 ,(1986) , 10.1016/S0140-6736(86)92368-8
F Vermeer, M L Simoons, F W Bär, J G Tijssen, R T van Domburg, P W Serruys, F W Verheugt, J C Res, C de Zwaan, A van der Laarse, Which patients benefit most from early thrombolytic therapy with intracoronary streptokinase Circulation. ,vol. 74, pp. 1379- 1389 ,(1986) , 10.1161/01.CIR.74.6.1379
Frits W. Bar, Frank Vermeer, Chris de Zwaan, Mercedes Ramentol, Simon Bratt, Maarten L. Simoons, Wim T. Hermens, Arnoud van der Laarse, Freek W.A. Verheugt, X. Hanno Krauss, Hein J.J. Wellens, Value of admission electrocardiogram in predicting outcome of thrombolytic therapy in acute myocardial infarction American Journal of Cardiology. ,vol. 59, pp. 6- 13 ,(1987) , 10.1016/S0002-9149(87)80060-7
F Van de Werf, J Vanhaecke, H de Geest, M Verstraete, D Collen, Coronary thrombolysis with recombinant single-chain urokinase-type plasminogen activator in patients with acute myocardial infarction. Circulation. ,vol. 74, pp. 1066- 1070 ,(1986) , 10.1161/01.CIR.74.5.1066
J H Chesebro, G Knatterud, R Roberts, J Borer, L S Cohen, J Dalen, H T Dodge, C K Francis, D Hillis, P Ludbrook, Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge. Circulation. ,vol. 76, pp. 142- 154 ,(1987) , 10.1161/01.CIR.76.1.142
Geoffrey O Hartzler, Barry D Rumerford, David R McConahay, Warren L Johnson, Ben D McCallister, George M Gura, Robert C Conn, James E Crockett, Percutaneous transluminal coronary angioplasty with and without thrombolytic therapy for treatment of acute myocardial infarction American Heart Journal. ,vol. 106, pp. 965- 973 ,(1983) , 10.1016/0002-8703(83)90639-7