Treatment of non-small cell lung cancer patients with the trifunctional monoclonal antibody catumaxomab (anti-EpCAM × anti-CD3): a phase I study

作者: Martin Sebastian , Bernward Passlick , Hilke Friccius-Quecke , Michael Jäger , Horst Lindhofer

DOI: 10.1007/S00262-007-0310-7

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摘要: … Thus, inhibition of EpCAM expression leads to a strong decrease in proliferation and … directed to EpCAM and the T cell marker CD3 (anti-EpCAM × anti-CD3). While binding to EpCAM-…

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