Cost-effectiveness of dual maternal HIV and syphilis testing strategies in high and low HIV prevalence countries: a modelling study.
作者： Patricia J Rodriguez , D Allen Roberts , Julianne Meisner , Monisha Sharma , Morkor Newman Owiredu
DOI: 10.1016/S2214-109X(20)30395-8
关键词:
摘要: Summary Background Dual HIV and syphilis testing might help to prevent mother-to-child transmission (MTCT) of through increased case detection treatment. We aimed model assess the cost-effectiveness dual during antenatal care in four countries with varying prevalence. Methods In this modelling study, we developed Markov models pregnant women estimate costs infant health outcomes maternal at first visit individual tests (base case) a rapid diagnostic test (scenario one). additionally evaluated retesting late delivery either two) or diagnosis three). modelled countries: South Africa, Kenya, Colombia, Ukraine. Strategies an incremental ratio (ICER) less than country-specific threshold (US$500 $750 $3000 $1000 Ukraine) per disability-adjusted life-year averted were considered cost-effective. Findings Routinely offering was cost-saving compared base all (ICER: –$26 Kenya,–$559 –$844 –$454 Ukraine). Retesting three) cost-effective scenario one $270 $260 $2207 $205 Interpretation Incorporating can be across Countries should consider incorporating as support efforts eliminate MTCT syphilis. Funding WHO, US Agency for International Development, Bill & Melinda Gates Foundation.
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