Traditional medicinal plants of Thailand. XVII. Biologically active constituents of Plumeria rubra.

作者: Matthias O. Hamburger , Geoffrey A. Cordell , Nijsiri Ruangrungsi

DOI: 10.1016/0378-8741(91)90091-Q

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摘要: The compounds 1-6 were isolated from the heartwood of Plumeria rubra, following bioactivity-directed fractionation. Plumericin 1 and isoplumericin 2 displayed molluscicidal, cytotoxic antibacterial activity, 4-hydroxyacetophenone 3 was weakly cytotoxic, whereas remaining glycosidic isolates (plumieride, 4; 13-O-coumaroylplumieride, 5; protoplumericine A, 6) inactive in all test systems.

参考文章(20)
Geoffrey A. Cordell, Nujsiri Ruangrungsi, Gulacti Topcu, Chun-Tao Che, Iridolactones fromAlyxia reinwardti Phytochemistry. ,vol. 29, pp. 3197- 3199 ,(1990) , 10.1016/0031-9422(90)80184-I
FUMIKO ABE, TOMOJIRO MORI, TATSUO YAMAUCHI, Iridoids of apocynaceae. III. Minor iridoids from Allamanda neriifolia. Chemical & Pharmaceutical Bulletin. ,vol. 32, pp. 2947- 2956 ,(1984) , 10.1248/CPB.32.2947
Eduardo Quisumbing, Medicinal plants of the Philippines. Department of Agriculture and Commerce, Philippine Islands Technical Bulletin.. ,(1951)
A. Marston, K. Hostettmann, K. E. Mott, Plant molluscicide research - an update. Plant molluscicides. Papers presented at a meeting of the Scientific Working Group on Plant Molluscicides, UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva, Switzerland, 31 January to 2 February, 1983.. pp. 299- 320 ,(1987)
Barry M. Trost, James M. Balkovec, Michael K. T. Mao, A total synthesis of plumericin, allamcin and allamandin. Part 2. A biomimetic strategy Journal of the American Chemical Society. ,vol. 108, pp. 4974- 4983 ,(1986) , 10.1021/JA00276A044
S. Morris. Kupchan, Thomas J. Giacobbe, Ira S. Krull, S. M. Thomas, M. Allan. Eakin, Dyral C. Fessler, Tumor inhibitors. LVII. Reaction of endocyclic .alpha.,.beta.-unsaturated .gamma.-lactones with thiols Journal of Organic Chemistry. ,vol. 35, pp. 3539- 3543 ,(1970) , 10.1021/JO00835A078
FUMIKO ABE, RONG-FU CHEN, TATSUO YAMAUCHI, Minor Iridoids from the Roots of Plumeria acutifolia Chemical & Pharmaceutical Bulletin. ,vol. 36, pp. 2784- 2789 ,(1988) , 10.1248/CPB.36.2784
Margaretha Leven, Dirk Berghe, Francis Mertens, Arnold Vlietinck, Edmond Lammens, Screening of higher plants for biological activities. I. Antimicrobial activity. Planta Medica. ,vol. 36, pp. 311- 321 ,(1979) , 10.1055/S-0028-1097277
Leonardus BS Kardono, Soefjan Tsauri, Kosasih Padmawinata, John M Pezzuto, A Douglas Kinghorn, None, Cytotoxic constituents of the bark of Plumeria rubra collected in Indonesia. Journal of Natural Products. ,vol. 53, pp. 1447- 1455 ,(1990) , 10.1021/NP50072A008