Three-dimensional printing-based electro-millifluidic devices for fabricating multi- compartment particles

摘要: In this work, we demonstrate the use of stereolithographic 3D printing to fabricate millifluidic devices, which are used engineer particles with multiple compartments. As design is directly transferred actual prototype, method accommodates millimeter-scaled features that difficult achieve by either lithographic-based microfabrication or traditional macrofabrication techniques. We exploit approach produce networks deliver fluidic components. By taking advantage laminar flow, components can form liquid jets distinct patterns, and each pattern has clear boundaries between phases. Afterwards, droplets controlled size fabricated spraying jet in an electric field, subsequently converted after a solidification step. demonstration, calcium alginate structures (1) slice-by-slice lamellae, (2) concentric core-shells, (3) petals surrounding particle centers. Furthermore, hybrid combining two more above also obtained. These compartmentalized impart spatially dependent functionalities properties. To show their applicability, various ingredients, including fruit juices, drugs, magnetic nanoparticles encapsulated different compartments as proof-of-concepts for applications, food, drug delivery, bioassays. Our printed electro-millifluidic represents convenient robust extend range functional particles.