Wavefront-guided LASIK with the Zyoptix 3.1 system for the correction of myopia and compound myopic astigmatism with 1-year follow-up: Clinical outcome and change in higher order aberrations

摘要: Objective To assess safety, efficacy, predictability, stability, and change in aberrations after wavefront-guided LASIK for myopia myopic astigmatism. Design Prospective, nonrandomized, self-controlled trial. Participants Wavefront-guided was performed 97 eyes a 1-year Treated had mean subjective manifest spherical equivalent (SE) of −5.22±2.07 diopters (D), with range −0.25 to −9.00 D 0 −3.25 Intervention After microkeratome cut, wavefront-based excimer ablation (Zyoptix 3.1) performed. The full treatment achieve emmetropia an early nomogram provided by the system manufacturer used all procedures. Main outcome measures Safety, stability were evaluated at 1, 3, 12 months postoperatively. Wavefront changes higher order (HOAs) 1 year determined pupil sizes 3.5 6 mm. Results At postoperatively, uncorrected visual acuity (VA) 20/20 or better 83% eyes, 20/40 98%. SE −0.25±0.43 D; it within 0.50 77% 1.0 95%. No eye lost ≥2 lines best spectacle-corrected VA (BSCVA) postoperatively; 40 gained line BSCVA, 5 2 lines. total HOA root square (RMS) increased on average factor 1.23±0.57 3.5-mm pupil; mm pupil, increase 1.52±0.36. reduction RMS observed 45.5% 20.6% 6-mm pupil. There significant primary aberration ( Z 4,0 ) 4.11±10.17 pupils 4.31±6.76 pupils. Conclusions using Zyoptix 3.1 is effective safe procedure Although close half HOAs could be reduced, there still undercorrection induction algorithm employed.