Different cumulative pregnancy rates in patients with repeated IVF‐ or ICSI cycles: possible influence of a male factor

作者: T. Stalf , J. Herrero , H. Turley , V. Hinz , B. Müller

DOI: 10.1111/J.1439-0272.1999.TB01402.X

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摘要: Summary The low rate of ongoing pregnancies in IVF cycles leads to a high number repeated couples with previously failed attempts. Therefore it would be helpful have prediction about the chance becoming pregnant cycle. In retrospective study data 4246 were analysed. Because pregnancy rates IVF- and ICSI are generally different, these two groups distinguished between outcome patients one, or more attempts was anlaysed. The per patient lower after (24.9%) than (32.9%), but similar even slightly increased one attempt. On other hand, there first (35.9%), had significantly (20.7%). Factors that known influence rate, such as stimulation protocol, oocyte quality transferred embryos, all groups. However, reduced embryo successive only observed patients. There might negative selection poor ICSI, possibly due an andrological factor. differences based on treatment indications, diseases predominant indication for ICSI. Although no correlation found changes conventional sperm parameters treated cycles, subgroup selected by repeatedly cycles. Chromosomal genetic disturbances spermatozoa this could reason failure.

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