作者: James L. Mulshine , Fred R. Hirsch
DOI: 10.1016/S0169-5002(03)00160-0
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摘要: Vast numbers of individuals who have stopped smoking already been exposed to critical amounts tobacco combustion products and are at significant risk developing lung cancer. If these diagnosed with regional or distant metastatic disease this condition is not typically curable existing systemic therapy. The need for more effective tools detect intervene early cancer detection a pressing public health priority. A major challenge in regard the development safe chemoprevention. factors influencing new clinical tool reviewed context trends care. Existing pharmaceutical efforts involved evaluation treatments advanced other disorders paper describes approaches tailor chemoprevention specifically biological, pharmacological anatomical realities most lethal