Primary care issues in patients with mental illness.

作者: Karen Gunning , Bernadette Kiraly , Jennifer Leiser

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摘要: Family physicians commonly care for patients with serious mental illness. Patients psychotic and bipolar disorders have more comorbid medical conditions higher mortality rates than without Many medications prescribed illness significant metabolic cardiovascular adverse effects. treated second-generation antipsychotics should receive preventive counseling treatment obesity, hyperglycemia, diabetes, hyperlipidemia. First- been associated QT prolongation. common can interact antipsychotics, increasing the risk of cardiac arrhythmias sudden death. Drug interactions also lead to increased effects, or decreased drug levels, toxicity, failure. Physicians carefully consider risks benefits antipsychotic medications, patient be coordinated between primary health professionals prevent

参考文章(36)
Daniel E. Casey, Dyslipidemia and atypical antipsychotic drugs. The Journal of Clinical Psychiatry. ,vol. 65, pp. 27- 35 ,(2004)
Trevor I. Prior, Glen B. Baker, Interactions between the cytochrome P450 system and the second-generation antipsychotics. Journal of Psychiatry & Neuroscience. ,vol. 28, pp. 99- 112 ,(2003)
Mark Olfson, Steven C. Marcus, Patricia Corey-Lisle, A.V. Tuomari, Patricia Hines, Gilbert J. L’Italien, Hyperlipidemia Following Treatment With Antipsychotic Medications American Journal of Psychiatry. ,vol. 163, pp. 1821- 1825 ,(2006) , 10.1176/AJP.2006.163.10.1821
Gerard Boehm, Judith A Racoosin, Thomas P Laughren, Russell Katz, None, Consensus Development Conference on Antipsychotic Drugs and Obesity and Diabetes Response to consensus statement Diabetes Care. ,vol. 27, pp. 2088- 2089 ,(2004) , 10.2337/DIACARE.27.8.2088-A
Donald C. Goff, Corinne Cather, A. Eden Evins, David C. Henderson, Oliver Freudenreich, Paul M. Copeland, Michael Bierer, Kenneth Duckworth, Frank M. Sacks, Medical Morbidity and Mortality in Schizophrenia The Journal of Clinical Psychiatry. ,vol. 66, pp. 183- 194 ,(2005) , 10.4088/JCP.V66N0205
Mayur M. Desai, Robert A. Rosenheck, Benjamin G. Druss, Jonathan B. Perlin, Mental Disorders and Quality of Diabetes Care in the Veterans Health Administration American Journal of Psychiatry. ,vol. 159, pp. 1584- 1590 ,(2002) , 10.1176/APPI.AJP.159.9.1584
D. M. Taylor, R. McAskill, Atypical antipsychotics and weight gain--a systematic review. Acta Psychiatrica Scandinavica. ,vol. 101, pp. 416- 432 ,(2000) , 10.1034/J.1600-0447.2000.101006416.X
Margaret T. Susce, Noemi Villanueva, Francisco J. Diaz, Jose de Leon, Obesity and Associated Complications in Patients With Severe Mental Illnesses The Journal of Clinical Psychiatry. ,vol. 66, pp. 167- 173 ,(2005) , 10.4088/JCP.V66N0203
Neil B. Sandson, Scott C. Armstrong, Kelly L. Cozza, An overview of psychotropic drug-drug interactions. Psychosomatics. ,vol. 46, pp. 464- 494 ,(2005) , 10.1176/APPI.PSY.46.5.464
Julie Kreyenbuhl, Faith B. Dickerson, Deborah R. Medoff, Clayton H. Brown, Richard W. Goldberg, LiJuan Fang, Karen Wohlheiter, Leena P. Mittal, Lisa B. Dixon, Extent and management of cardiovascular risk factors in patients with type 2 diabetes and serious mental illness. Journal of Nervous and Mental Disease. ,vol. 194, pp. 404- 410 ,(2006) , 10.1097/01.NMD.0000221177.51089.7D