GSK-3 and Wnt Markers of Neurodevelopmental Abnormalities in Schizophrenia
作者： Nitsan Kozlovsky , Rh Belmaker , Galila Agam
DOI: 10.1007/978-1-4757-3631-1_15
关键词:
摘要: The Neurodevelopmental Hypothesis of schizophrenia suggests that interaction between genetic and environmental events occurring during critical early periods in neuronal growth may negatively influence the way by which nerve cells are laid down, differentiated selectively culled apoptosis. Recent advances offer insights into regulation brain development. Wnt family genes plays a central role normal Activation cascade leads to inactivation glycogen synthase kinase-3s (GSK-3s), accumulation activation scatenin expression involved possible aberrant GSK-3 etiology is discussed.
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