Stability of CT scan findings in schizophrenia: results of an 8 year follow-up study.

摘要: Earlier cross-sectional studies have suggested that CT findings of ventricular enlargement and increased cortical markings in schizophrenic patients are not progressive, but individual rarely been followed prospectively. Fifteen with chronic schizophrenia were rescanned on the same model machine after 7 to 9 years continuous illness and, seven cases, hospitalisation. It was possible demonstrate significant changes either ventricular-brain ratio or frontal atrophy scores. These results suggest pathologic process responsible for is static affected by 8 neuroleptic medication institutionalisation.