Identification and management of hepatitis C patients in primary care clinics

作者: Thomas M Shehab , Mauricio Orrego , Renu Chunduri , Anna SF Lok , None

DOI: 10.1016/S0002-9270(02)06053-7

关键词:

摘要: OBJECTIVE: Previous survey-based research suggested that hepatitis C patients receive suboptimal care in primary settings. The aim of our study was to define the actual level clinics. METHODS: Medical records 229 antibodypositive (group 1), antibody-negative 2), and not tested for antibody 3) were reviewed assess indications testing subsequent management referral antibody-positive diagnosed In addition, compliance physicians with screening guidelines assessed. RESULTS: Only 16% group 1 10% 2 based on physician-identified risk factors. 1% 3 had documented discussion factors during their initial visit a physician. majority appropriately evaluated clinics, most (77%) RNApositive elevated liver enzymes referred subspecialty care. Of 59 who underwent biopsy, 40% bridging fibrosis or cirrhosis. CONCLUSIONS: Hepatitis is rarely initiated clinics Interventions should be developed optimize early diagnosis as significant disease may present despite absence symptoms. (Am J Gastroenterol 2003;98:639 ‐ 644. © 2003 by Am. Coll. Gastroenterology)

参考文章(14)
J. M. Calvo Romero, J. M. Puerto Pica, Gastric adenocarcinoma and kidney transplantation Gastroenterología y Hepatología. ,vol. 21, pp. 260- ,(1998)
Michael W. Fried, Mitchell L. Shiffman, Rejender K. Reddy, Coleman Smith, George Marino, Femando Goncales, Dieter Haeussinger, Moises Diago, Giampietro Carosl, Jean-Pierre Zarski, Joseph Hoffman, Jian Yu, Pegylated (40kDa) interferon alfa-2a (PEGASYS®) in combination with ribavirin: Efficacy and safety results from a phase III, randomized, actively-controlled, multicenter study Gastroenterology. ,vol. 120, pp. A55- ,(2001) , 10.1016/S0016-5085(08)80271-5
Thelma E. Wiley, Mary McCarthy, Lama Breidi, Monica McCarthy, Thomas J. Layden, Impact of alcohol on the histological and clinical progression of Hepatitis C infection Hepatology. ,vol. 28, pp. 805- 809 ,(1998) , 10.1002/HEP.510280330
Michael P Manns, Matthias J Bahr, Recurrent autoimmune hepatitis after liver transplantation—when non-self becomes self Hepatology. ,vol. 32, pp. 868- 870 ,(2000) , 10.1053/JHEP.2000.19149
Satoru Kakizaki, Hitoshi Takagi, Masami Murakami, Hisashi Takayama, Masatomo Mori, HLA antigens in patients with interferon-α-induced autoimmune thyroid disorders in chronic hepatitis C Journal of Hepatology. ,vol. 30, pp. 794- 800 ,(1999) , 10.1016/S0168-8278(99)80131-7
D. E. Nicklin, C. Schultz, C. M. Brensinger, J. P. Wilson, Current Care of Hepatitis C-Positive Patients by Primary Care Physicians in an Integrated Delivery System Journal of The American Board of Family Practice. ,vol. 12, pp. 427- 435 ,(1999) , 10.3122/JABFM.12.6.427
Thomas M. Shehab, Seema S. Sonnad, Mark Jeffries, Naresh Gunaratnum, Anna S. Lok, Current practice patterns of primary care physicians in the management of patients with hepatitis C. Hepatology. ,vol. 30, pp. 794- 800 ,(1999) , 10.1002/HEP.510300328
Thierry Poynard, Patrick Marcellin, Samuel S Lee, Christian Niederau, Gerald S Minuk, Gaetano Ideo, Vincent Bain, Jenny Heathcote, Stefan Zeuzem, Christian Trepo, Janice Albrecht, None, Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus The Lancet. ,vol. 352, pp. 1426- 1432 ,(1998) , 10.1016/S0140-6736(98)07124-4