Epidemiologic and clinical evaluation of thyroid cancer in children from the Gomel region (Belarus)

摘要: This study reviews the epidemiology of thyroid cancer during childhood from environs Gomel in Belarus and clinical data 64 children aged 4 to 16 years this area who had been diagnosed with differentiated carcinoma following nuclear accident Chernobyl. One case (aged < 15 at diagnosis) was observed period 1981-1985 (rate = 0.5; expressed as annual averages per million under age region identified) before Chernobyl accident. Twenty-one cases were 1986-1990 10.5) 143 97) 1991-1994 after During first 7 months 1995, there 33 more children. Three born since 1986 region. A total reviewed by us May November 1994. The female/male ratio 1.4:1.0. At time diagnosis mean 9.4 +/- 2.8 years, their 3.8 2.4 years. More than 90% patients less 6 3 still utero latency between 5.6 1.5 Their ages significantly correlated (p 0.001); no significant correlation each child latent onset carcinoma. aggressiveness tumor, evaluated on basis T stage, lymph node status, lung metastases, did not correlate or susceptibility carcinogenetic effects radiation, particularly life (< 5 years) has clearly demonstrated. However, appears be tumor patients.