Portrait of the PI3K/AKT pathway in colorectal cancer ☆
作者： Stine Aske Danielsen , Peter Wold Eide , Arild Nesbakken , Tormod Guren , Edward Leithe
DOI: 10.1016/J.BBCAN.2014.09.008
关键词:
摘要: … PI3K/AKT signaling leads to reduced apoptosis, stimulates cell growth and increases proliferation. Under normal conditions, PI3K/AKT … Genetic aberrations leading to PI3K/AKT hyper-…
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utsystem.edu 参考文章(290)
Charis Eng, Jessica Mester, When Overgrowth Bumps Into Cancer: The PTEN‐Opathies American Journal of Medical Genetics Part C-seminars in Medical Genetics. ,vol. 163, pp. 114- 121 ,(2013) , 10.1002/J.1552-4876.2013.31364.X
K. Al-Kuraya, H. Novotny, P. Bavi, A. K Siraj, S. Uddin, A. Ezzat, N. A. Sanea, F. Al-Dayel, H. Al-Mana, S. S Sheikh, M. Mirlacher, C. Tapia, R. Simon, G. Sauter, L. Terracciano, L. Tornillo, HER2, TOP2A, CCND1, EGFR and C‐MYC oncogene amplification in colorectal cancer Journal of Clinical Pathology. ,vol. 60, pp. 768- 772 ,(2006) , 10.1136/JCP.2006.038281
A. K. Rustgi, The genetics of hereditary colon cancer Genes & Development. ,vol. 21, pp. 2525- 2538 ,(2007) , 10.1101/GAD.1593107
Charles J. Vaske, Stephen C. Benz, J. Zachary Sanborn, Dent Earl, Christopher Szeto, Jingchun Zhu, David Haussler, Joshua M. Stuart, Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM Bioinformatics. ,vol. 26, pp. 237- 245 ,(2010) , 10.1093/BIOINFORMATICS/BTQ182
S. R. Hamilton, BRAF Mutation and Microsatellite Instability Status in Colonic and Rectal Carcinoma: Context Really Does Matter Journal of the National Cancer Institute. ,vol. 105, pp. 1075- 1077 ,(2013) , 10.1093/JNCI/DJT189
James F. Reid, Viktorija Sokolova, Eugenio Zoni, Andrea Lampis, Sara Pizzamiglio, Claudia Bertan, Susanna Zanutto, Federica Perrone, Tiziana Camerini, Gianfrancesco Gallino, Paolo Verderio, Ermanno Leo, Silvana Pilotti, Manuela Gariboldi, Marco A. Pierotti, miRNA Profiling in Colorectal Cancer Highlights miR-1 Involvement in MET-Dependent Proliferation Molecular Cancer Research. ,vol. 10, pp. 504- 515 ,(2012) , 10.1158/1541-7786.MCR-11-0342
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway, Highly Recurrent TERT Promoter Mutations in Human Melanoma Science. ,vol. 339, pp. 957- 959 ,(2013) , 10.1126/SCIENCE.1229259
Shuji Ogino, Jeffrey A Meyerhardt, Natsumi Irahara, Donna Niedzwiecki, Donna Hollis, Leonard B Saltz, Robert J Mayer, Paul Schaefer, Renaud Whittom, Alexander Hantel, Al B Benson III, Richard M Goldberg, Monica M Bertagnolli, Charles S Fuchs, Cancer and Leukemia Group B, North Central Cancer Treatment Group, Canadian Cancer Society Research Institute, Southwest Oncology Group, KRAS Mutation in Stage III Colon Cancer and Clinical Outcome Following Intergroup Trial CALGB 89803 Clinical Cancer Research. ,vol. 15, pp. 7322- 7329 ,(2009) , 10.1158/1078-0432.CCR-09-1570
F Cappuzzo, M Varella-Garcia, G Finocchiaro, M Skokan, S Gajapathy, C Carnaghi, L Rimassa, E Rossi, C Ligorio, L Di Tommaso, AJ Holmes, L Toschi, Giovanni Tallini, A Destro, M Roncalli, A Santoro, PA Jänne, None, Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients. British Journal of Cancer. ,vol. 99, pp. 83- 89 ,(2008) , 10.1038/SJ.BJC.6604439
Jürgen Cox, Matthias Mann, None, Quantitative, High-Resolution Proteomics for Data-Driven Systems Biology Annual Review of Biochemistry. ,vol. 80, pp. 273- 299 ,(2011) , 10.1146/ANNUREV-BIOCHEM-061308-093216