RefSeq and LocusLink: NCBI gene-centered resources.

摘要: Thousands of genes have been painstakingly identified and characterized a few at time. Many thousands more are being predicted by large scale cDNA genomic sequencing projects, with levels evidence ranging from supporting mRNA sequence comparative genomics to computing ab initio models. This, coupled the burgeoning scientific literature, makes it critical comprehensive directory for reference sequences key genomes. The NCBI provides two resources, LocusLink RefSeq, meet these needs. organizes information around generate central hub accessing gene-specific fruit fly, human, mouse, rat zebrafish. RefSeq standards genomes, transcripts proteins; mouse RefSeqs, their corresponding proteins, discussed here. Together, provide non-redundant view other loci support research on gene families, variation, expression genome annotation. Additional about is available http://www.ncbi.nlm.nih.gov/LocusLink/.