Cardioprotective phosphonates and malonates
作者： Wasimul Haque
DOI:
关键词:
摘要: The present invention provides for pyridoxine phosphonate analogues such as, example, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)alkylphosphonates, and (2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)azaalkylphosphonates) to malonate analogues, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridylmethyl)malonates), pharmaceutical compositions, methods treatment of cardiovascular related diseases, diabetes mellitus diseases.
lens.org 参考文章(151)
Andre Esanu, Anti-depressive vincamine pyridoxal-5-phosphate ,(1977)
Willem J. Serfontein, Method and composition for supplementing vitamin B6 where the PN-PLP pathway is disturbed ,(1990)
Andre Esanu, Papaverine monopyridoxal phosphate ,(1973)
A Z Karakilçik, A Sermet, M Aybak, M O Ayyildiz, Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Drug Research. ,vol. 45, pp. 1271- 1273 ,(1995)
SC Yan, Ronald J Uhing, Richard F Parrish, David E Metzler, Donald J Graves, None, A role for pyridoxal phosphate in the control of dephosphorylation of phosphorylase a. Journal of Biological Chemistry. ,vol. 254, pp. 8263- 8269 ,(1979) , 10.1016/S0021-9258(19)86885-0
Massimo Baldacci, Therapeutic use of pyridoxine pyrrolidone carboxylate ,(1994)
Raymond Bennett, Alfred Burger, W. W. Umbreit, Vitamin B6--phosphonic acids. Journal of Medicinal Chemistry. ,vol. 1, pp. 213- 221 ,(1959) , 10.1021/JM50004A002
Francesco Fici, Use of pyridoxine α-ketoglutarate in the prophylaxis of hyperlacticacidaemia ,(1981)
Donald J. Graves, Richard F. Parrish, Ronald J. Uhing, Walter Korytnyk, PYRIDOXAL PHOSPHATE ANALOGS AND COENZYME FUNCTION IN GLYCOGEN PHOSPHORYLASE Regulatory Mechanisms of Carbohydrate Metabolism#R##N#11th Meeting Copenhagen 1977. pp. 195- 204 ,(1978) , 10.1016/B978-0-08-022623-1.50023-X
Dan Sibalis, Method for enhancing transdermal drug delivery of electrical drug applicators ,(1992)