Unnatural Nucleosides with Unusual Base Pairing Properties
作者： Donald E. Bergstrom
DOI: 10.1002/0471142700.NC0104S37
关键词:
摘要: Synthetic modified nucleosides designed to pair in unusual ways with natural nucleobases have many potential applications nucleic acid biochemistry. This overview lays the foundation for future protocol units on synthesis and application of unnatural bases, particular emphasis base analogs that mimic bases size, shape, biochemical processing. Topics covered including pairs alternative H-bonding schemes, hydrophobic pairs, degenerate universal nucleosides, triplex constituents.
sci-hub.se 参考文章(173)
Yasutoshi KAWASE, Shigenori IWAI, Eiko OHTSUKA, Synthesis and Thermal Stability of Dodecadeoxyribonucleotides Containing Deoxyinosine Pairing with Four Major Bases Chemical & Pharmaceutical Bulletin. ,vol. 37, pp. 599- 601 ,(1989) , 10.1248/CPB.37.599
Tracy J. Matray, Eric T. Kool, A specific partner for abasic damage in DNA Nature. ,vol. 399, pp. 704- 708 ,(1999) , 10.1038/21453
Shane Crotty, David Maag, Jamie J. Arnold, Weidong Zhong, Johnson Y. N. Lau, Zhi Hong, Raul Andino, Craig E. Cameron, The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen. Nature Medicine. ,vol. 6, pp. 1375- 1379 ,(2000) , 10.1038/82191
E Ohtsuka, S Matsuki, M Ikehara, Y Takahashi, K Matsubara, An alternative approach to deoxyoligonucleotides as hybridization probes by insertion of deoxyinosine at ambiguous codon positions. Journal of Biological Chemistry. ,vol. 260, pp. 2605- 2608 ,(1985) , 10.1016/S0021-9258(18)89400-5
H. Yu, R. Eritja, L.B. Bloom, M.F. Goodman, Ionization of bromouracil and fluorouracil stimulates base mispairing frequencies with guanine Journal of Biological Chemistry. ,vol. 268, pp. 15935- 15943 ,(1993) , 10.1016/S0021-9258(18)82342-0
S Uesugi, Y Oda, M Ikehara, Y Kawase, E Ohtsuka, Identification of I:A mismatch base-pairing structure in DNA. Journal of Biological Chemistry. ,vol. 262, pp. 6965- 6968 ,(1987) , 10.1016/S0021-9258(18)48187-2
Junlin He, Frank Seela, Base Pairing of 8‐Aza‐7‐deazapurine‐2,6‐diamine Linked via the N(8)‐Position to the DNA Backbone: Universal Base‐Pairing Properties and Formation of Highly Stable Duplexes when Alternating with dT Helvetica Chimica Acta. ,vol. 85, pp. 1340- 1354 ,(2002) , 10.1002/1522-2675(200205)85:5<1340::AID-HLCA1340>3.0.CO;2-H
Eric T. Kool, Replication of non-hydrogen bonded bases by DNA polymerases: A mechanism for steric matching Biopolymers. ,vol. 48, pp. 3- 17 ,(1998) , 10.1002/(SICI)1097-0282(1998)48:1<3::AID-BIP2>3.0.CO;2-7
T. Ohtsuki, M. Kimoto, M. Ishikawa, T. Mitsui, I. Hirao, S. Yokoyama, Unnatural base pairs for specific transcription Proceedings of the National Academy of Sciences of the United States of America. ,vol. 98, pp. 4922- 4925 ,(2001) , 10.1073/PNAS.091532698
F. Hill, D. Loakes, D. M. Brown, Polymerase recognition of synthetic oligodeoxyribonucleotides incorporating degenerate pyrimidine and purine bases. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 4258- 4263 ,(1998) , 10.1073/PNAS.95.8.4258