Stem Cell Plasticity: Validation Versus Valedictory

作者: Neil David Theise

DOI: 10.1007/978-3-540-77755-7_16

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摘要: The field of stem cell plasticity, by which most commentators and investigators mean plasticity adult cells, was opened to great fanfare with the publication three papers in Science last 2 years prior millennium. This trio, taken together, trumpeted as “Breakthrough Year” for 1999 showed that cells deriving from one organ were not only restricted producing (so, e.g., marrow-derived could become skeletal muscle) but also their embryonic germ layer origin (neural produced blood marrowderived liver) [1–3].

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