Relationship between longitudinal and radial contractility in subclinical diabetic heart disease.

摘要: Subclinical left ventricular (LV) dysfunction may be identified by reduced longitudinal contraction. We sought to define the effects of subclinical LV on radial contractility in 53 patients with diabetes mellitus no hypertrophy, normal ejection fraction and ischaemia as assessed dobutamine echocardiography, comparison age-matched controls. Radial peak myocardial systolic velocity (Sm) early diastolic (Em), strain rate were measured mid-posterior mid-anteroseptal walls parasternal views each variable was averaged for individual (radial contractility). These variables also apical long-axis view (longitudinal Mean Sm, significantly increased diabetic (2.9 +/- 0.6 cm/s, 28 5% 1.8 0.4 s(-1) respectively) compared controls (2.4 0.7 23 4% 1.6 0.3 respectively; all P<0.001), but there difference Em (3.3 1.2 3.1 1.1 P=not significant). In contrast, Em, lower (3.6 4.3 21 than (4.3 1.0 5.7 2.3 26 1.9 P< or =0.001). Thus appears compensate occurring absence hypertrophy.