Behavioral Analysis of the Transplantation Phenomenon within a Motor and Sensory System

摘要: Traditionally, research in neuropsychology has taken the following two directions: (1) removal of a neural structure by surgical means ablation or electrolytic lesion and study concomitant deficit loss function, (2) stimulation to immediately response. These approaches, being complementary nature, have provided great insight into problems sturcture/function brain. In recent years, on transplantation initiated Das his associates (Das 1975, Hallas 1978) seems offer new ways approaching neuropsychology. Potentially, there are at least different directions that may be pursued. First, chemical change host animal induce functional abnormality deficit, followed tissue recovery from abnormal deficient function. Second, with high growth potential order replace large volume specific region brain transplant, behavior these animals, this turn, transplant The first approach been used Bjorklund Stenevi (1979). But second less widely employed other than for work our laboratories (Wallace 1982). This exploring “functional compensation” plasticity” tissues. It can best investigated if heterotopic conditions (e.g., embryonic neocortical cerebella animals). Such transplants intraparenchymal completely integrated brain, no pathological reactions even after 2 more years transplantation.