Newer strategies for anemia prevention in hemodialysis.

摘要: Anemia prevention for hemodialysis relies primarily on supplemental erythropoietin (EPO) and intravenous iron (IV-iron). The doses of EPO utilized are somewhat higher than normal endogenous rates production in healthy subjects, the amount IV-iron used to boost red blood cell (RBC) may be greater amounts erythropoiesis. might more efficiently if two fundamental problems were solved management dialysis patients: better vitamin C status, avoidance chronic inflammation. low levels plasma commonly observed patients restrict mobilization stored from reticuloendothelial system (RES), inflammation has a very similar effect. impact concurrent causes large stored, with relatively inefficient utilization Vitamin intake is often restricted because C-rich foods, concerns about oxalosis. Inflammation feature renal disease, which compounded by infections use catheters. Research strategies improve status decrease would lead EPO, could have parallel benefits long-term health hemodialysis.