A six-week study to evaluate the anti-calculus efficacy of a chewing gum containing pyrophosphate and tripolyphosphate.

摘要: OBJECTIVE A six-week, double-blind, cross-over clinical study was conducted to compare the effect of a new chewing gum containing pyrophosphate (1%) and tripolyphosphate (1%), versus control on supragingival calculus deposits. METHODOLOGY Twenty-eight adult subjects (mean age 34 +/- 8 years) who entered were given full oral prophylaxis assigned chew two pieces gum, four times day for five minutes. The either test or placebo randomly directed their six weeks. All participants also received 12-week supply sodium fluoride (0.32%) dentifrice (Colgate). They then scored deposits using modified Volpe-Manhold Calculus Index (VMI) by same examiners. At end first weeks, second used alternate six-week period time. again completed. RESULTS results demonstrated mean VMI 3.65 2.82 group, 4.24 3.25 group. This difference significant with paired sample t-test (p < 0.001). CONCLUSION These indicated that reduced formation 13.9%, compared gum.