Neonatal development altered by maternal sulfur dioxide exposure.

摘要: Sulfur dioxide (SO2) is one of the commonly encountered environmental contaminants. Experiments were carried out to test for neonatal behavioral alterations associated with maternal SO2 exposure. Pregnant CD-I mice exposed 0, 32, or 65 PPM in chambers from gestation day 7 18 (plug = 1). The air flow was set at 500 ml/min. Food and water available all times. dams allowed deliver development pups studied. Maternal exposure did not affect mean number live born/litter; however, high level significantly decreased pup weight on 1 birth. both levels increased time required righting reflex birth negative geotaxis 10 aerial score 12 data suggest that can neuromuscular coordination may produce deficits functional capability developing offspring. appear be