Methods and kits for inducing a ctl response using a prime boost regimen

作者: Erik Depla , Der Aa Annegret Van

DOI:

关键词:

摘要: The present invention relates to the generation of a T cell response against target antigen using polypeptide comprising polyepitope construct as priming composition in prime boostregimen.

参考文章(15)
Jai Kumar Duraiswamy, Denis James Moss, Scott Anthony Thomson, Treatment of epstein-barr virus-associated diseases IP Australia. ,(2006)
Don Diamond, Fusion peptide HIV vaccines ,(2004)
Alessandro Sette, Scott Southwood, John Sidney, Identification of broadly reactive dr restricted epitopes ,(1999)
Michael J. Palmowski, Edward Man-Lik Choi, Vincenzo Cerundolo, Materials and methods relating to improved vaccination strategies ,(2002)
Brian D. Livingston, Lilia Maria Babe, Lawrence M. DeYoung, Mark J. Newman, Scott D. Power, Yiyou Chen, Manley T. F. Huang, Robert Chesnut, Alessandro Sette, Optimized multi-epitope constructs and uses thereof ,(2003)
Thuy T.T. Le, Debbie Drane, Jim Malliaros, John C. Cox, Linda Rothel, Martin Pearse, Tonia Woodberry, Joy Gardner, Andreas Suhrbier, Cytotoxic T cell polyepitope vaccines delivered by ISCOMs. Vaccine. ,vol. 19, pp. 4669- 4675 ,(2001) , 10.1016/S0264-410X(01)00243-2
Alexey M. Eroshkin, Elena A. Karginova, Irina P. Gileva, Alexander S. Lomakin, Leonid R. Lebedev, Tatiana P. Kamyinina, Alexander V. Pereboev, Georgy M. Ignat'ev, Design of four-helix bundle protein as a candidate for HIV vaccine "Protein Engineering, Design and Selection". ,vol. 8, pp. 167- 173 ,(1995) , 10.1093/PROTEIN/8.2.167
V.B. Loktev, A.A. Ilyichev, A.M. Eroshkin, L.I. Karpenko, A.G. Pokrovsky, A.V. Pereboev, V.A. Svyatchenko, G.M. Ignat'ev, M.I. Smolina, N.V. Melamed, C.D. Lebedeva, L.S. Sandakhchiev, Design of immunogens as components of a new generation of molecular vaccines Journal of Biotechnology. ,vol. 44, pp. 129- 137 ,(1996) , 10.1016/0168-1656(95)00089-5