Effects of Chitosan Oligosaccharide Supplementation on Blood Glucose, Lipid Components and Enzyme Activities in Hyperglycemic Rats
作者： Jong-Hwan Seong , Han-Soo Kim
DOI:
关键词:
摘要: Abstract The principal objective of this study was to assess the effects chitosan oligosaccharide supplementation on improve-ment blood glucose, lipid components and enzyme activities in serum streptozotocin(STZ, 55 ㎎/㎏ B.W., I.P. injection)-induced hyperglycemic rats fed experimental diets for 5 weeks. concentrations total cholesterol, atherosclerotic index, LDL, LDL-cholesterol, free cholesteryl ester ratio, triglycerides(TG) phospholipids(PL) were remarkably higher group(group BSW) STZ(I.P.)+chitosan ECW) than those control BW, basal diet+water). However TG PL lower ECW group BSW group, whereas ratio HDL-cholesterol concentration cholesterol group. alkaline phosphatase(ALP) aminotransferase(AST, ALT) results shown above suggested that effectively improves composition sera STZ-induced rats. Key words: oligosaccharide, components, activity, hyperglycemia.
koreascience.or.kr参考文章(24)
Riccardo A.A. Muzzarelli, Maria Weckx, Oscar Filippini, Fabio Sigon, Removal of trace metal ions from industrial waters, nuclear effluents and drinking water, with the aid of cross-linked N-carboxymethyl chitosan Carbohydrate Polymers. ,vol. 11, pp. 293- 306 ,(1989) , 10.1016/0144-8617(89)90004-0
Hong Keun Cho, Diabetes Mellitus and Disorder of Lipid Metabolism Journal of Korean Endocrine Society. ,vol. 21, pp. 101- 105 ,(2006) , 10.3803/JKES.2006.21.2.101
Z Madar, Effect of brown rice and soybean dietary fiber on the control of glucose and lipid metabolism in diabetic rats. The American Journal of Clinical Nutrition. ,vol. 38, pp. 388- 393 ,(1983) , 10.1093/AJCN/38.3.388
C. L. Lasko, B. M. Pesic, D. J. Oliver, Enhancement of the metal‐binding properties of chitosan through synthetic addition of sulfur‐ and nitrogen‐containing compounds Journal of Applied Polymer Science. ,vol. 48, pp. 1565- 1570 ,(1993) , 10.1002/APP.1993.070480908
Lars Lind, Bengt Vessby, Johan Sundström, The Apolipoprotein B/AI Ratio and the Metabolic Syndrome Independently Predict Risk for Myocardial Infarction in Middle-Aged Men Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 26, pp. 406- 410 ,(2005) , 10.1161/01.ATV.0000197827.12431.D0
Stanley Reitman, Sam Frankel, A Colorimetric Method for the Determination of Serum Glutamic Oxalacetic and Glutamic Pyruvic Transaminases American Journal of Clinical Pathology. ,vol. 28, pp. 56- 63 ,(1957) , 10.1093/AJCP/28.1.56
D. Knorr, Recovery and utilization of chitin and chitosan in food processing waste management Food Technology. ,vol. 45, pp. 114- 122 ,(1991)
Toshihiro MIURA, Masaru USAMI, Yoshiyuki TSUURA, Hitoshi ISHIDA, Yutaka SEINO, Hypoglycemic and hypolipidemic effect of chitosan in normal and neonatal streptozotocin-induced diabetic mice. Biological & Pharmaceutical Bulletin. ,vol. 18, pp. 1623- 1625 ,(1995) , 10.1248/BPB.18.1623
You-Jin Jeon, Se-Kwon Kim, Antitumor activity of chitosan oligosaccharides produced in ultrafiltration membrane reactor system Journal of Microbiology and Biotechnology. ,vol. 12, pp. 503- 507 ,(2002)
P. Vainio, P. K. J. Kinnunen, J. A. Virtanen, Lipoprotein lipase and hepatic endothelial lipase: their roles in plasma lipoprotein metabolism Atherosclerosis reviews. ,vol. 11, pp. 65- 105 ,(1983)