PEG-assisted two-component approach for the facile synthesis of 5-aryl-1,2,4-triazolidine-3-thiones under catalyst-free conditions
作者： Rathinam Ramesh , Appaswami Lalitha
DOI: 10.1039/C5RA07726E
关键词:
摘要: A straightforward and greener PEG-assisted protocol has been disclosed for the facile synthesis of 5-aryl-1,2,4-triazolidine-3-thiones via two-component reaction multifarious aromatic aldehydes thiosemicarbazides using very convenient neutral conditions. This methodology represents a sustainable approach rapid access to library diversity-oriented highly pure triazolidine scaffolds with broad substrate scope.
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