Radiation therapy at the end of life in patients with incurable nonsmall cell lung cancer

摘要: BACKGROUND: Receipt of chemotherapy at the end life (EOL) is considered an indicator poor quality care for medical oncology. The objective this study was to characterize use radiotherapy (RT) in patients with nonsmall cell lung cancer (NSCLC) during same period. METHODS: Treatment characteristics incurable NSCLC who received RT EOL, defined as within 14 days death, were analyzed from National Comprehensive Cancer Network Outcomes Database. RESULTS: Among 1098 died, 10% had EOL RT. Patients did and not receive similar terms sex, race, comorbid disease, Eastern Cooperative Oncology Group performance status. On multivariable logistic regression analysis, independent predictors receiving included stage IV disease (odds ratio [OR], 2.04; 95% confidence interval [CI], 1.09-3.83) or multiorgan involvement (OR, 1.75; CI, 1.08-2.84) diagnosis, age <65 years diagnosis 1.85; 1.21-2.83), treating institution 1.24-5.94; P ¼ .02). Nearly 50% recipients complete it, most commonly because death patient preference. CONCLUSIONS: In general, infrequently, delivered more younger advanced often completed planned. There also considerable variation its among institutions. Next steps include expanding research other cancers settings investigating clinical benefit such treatment. 2012;118:4339-45. V C 2012 American Society.