Fibrocytes: a unique cell population implicated in wound healing.

摘要: Following tissue damage, host wound healing ensues. This process requires an elaborate interplay between numerous cell types which orchestrate a series of regulated and overlapping events. These events include the initiation antigen-specific immune response, blood vessel formation, as well production critical extracellular matrix molecules, cytokines growth factors mediate repair closure. Connective fibroblasts are considered essential for successful healing; however, their origin remains mystery. A unique population, known fibrocytes, has been identified characterized. One features these blood-borne cells is ability to home sites damage. article reviews identification characterization summarizes potential role fibrocytes in steps wound-healing highlights fibrotic disease pathogenesis.