Phenolic compounds from the roots of Jordanian viper's grass, Scorzonera judaica.
作者： Roberta Cotugno , Alessandra Braca , Ammar Bader , Nunziatina De Tommasi
DOI: 10.1021/NP200143S
关键词:
摘要: Nine new phenolic compounds, 3S-hydrangenol 40-O-R-L-rhamnopyranoysl-(1-->3)-β-D-glucopyranoside (1), thunberginol F 7-O-β-D-glucopyranoside (2), 2-hydroxy-6-[2-(4-hydroxyphenyl)-2-oxo-ethyl]benzoic acid (3), 2-hydroxy-6-[2-(3,4-dihydroxyphenyl)-2-oxo-ethyl]benzoic (4), 2-hydroxy-6-[2-(3,4-dihydroxyphenyl-5-methoxy)-2-oxoethyl]benzoic (5), hydrangeic 40-O-β-D-glucopyranoside (6), E-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)dihydrofuran-2-one (7), Z-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)-2(3H)-furanone (8), and 4-[β-D-glucopyranosyl)hydroxy]-pinoresinol (9), nine known compounds were isolated from the roots of Scorzonera judaica. Structures 1-9 elucidated by mass spectrometry, extensive 1D 2D NMR spectroscopy, CD spectroscopy.All evaluated for cytotoxic activity.
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