Demonstration of a β-casomorphin immunoreactive material in the plasma of newborn calves after milk intake

作者: Martin Umbach , Hansjörg Teschemacher , Karina Praetorius , Richard Hirschhäuser , Hartwig Bostedt

DOI: 10.1016/0167-0115(85)90063-1

关键词:

摘要: Abstract Blood was collected from newborn calves before and after their first milk intake birth; extracts of plasma were assayed by radioimmunoassay for the presence β-casomorphin-7 immunoreactive materials. No β-casomorphin immunoreactivity found in samples ingestion; however, ingestion a material detected. Chromatographic characterization showed that this not identical with but might rather represent precursor thereof. The proved resistant to enzymatic attack during 30-min incubation period at 37°C calves, whereas degraded under these conditions. A physiological significance eventually cleaved such any site mammal is suggested.

参考文章(28)
Victor Brantl, Hansjörg Teschemacher, Julia Bläsig, Agnes Henschen, Friedrich Lottspeich, Opioid activities of β-casomorphins Life Sciences. ,vol. 28, pp. 1903- 1909 ,(1981) , 10.1016/0024-3205(81)90297-6
FC GREENWOOD, WM HUNTER, JS GLOVER, THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY Biochemical Journal. ,vol. 89, pp. 114- 123 ,(1963) , 10.1042/BJ0890114
V. Schusdziarra, R. Schick, A. Holland, A. de la Fuente, J. Specht, V. Maier, V. Brantl, E.F. Pfeiffer, Effect of opiate-active substances on pancreatic polypeptide levels in dogs Peptides. ,vol. 4, pp. 205- 210 ,(1983) , 10.1016/0196-9781(83)90115-8
George Scatchard, The Attractions of Proteins for Small Molecules and Ions Annals of the New York Academy of Sciences. ,vol. 51, pp. 660- 672 ,(1949) , 10.1111/J.1749-6632.1949.TB27297.X
John E. Morley, Food Peptides JAMA. ,vol. 247, pp. 2379- 2380 ,(1982) , 10.1001/JAMA.1982.03320420029026
Laurence W. Haynes, Opioid systems and the developing brain Trends in Pharmacological Sciences. ,vol. 5, pp. 454- 456 ,(1984) , 10.1016/0165-6147(84)90503-0
J. Panksepp, L. Normansell, S. Siviy, J. Rossi, A.J. Zolovick, Casomorphins reduce separation distress in chicks. Peptides. ,vol. 5, pp. 829- 831 ,(1984) , 10.1016/0196-9781(84)90030-5