Examining the incidence of human papillomavirus-associated head and neck cancers by race and ethnicity in the U.S., 1995-2005.

摘要: Background Head and neck cancer (HNC) incidence, mortality survival rates vary by sex race, with men African Americans disproportionately affected. Risk factors for HNC include tobacco alcohol exposure, a recent implication of human papillomavirus (HPV) in the pathogenesis HNC. This study describes epidemiology United States, examining variation age, sex, race/ethnicity potential HPV-association. Methods We used North American Association Central Cancer Registries (NAACCR) America (CINA) Deluxe Analytic Data to analyze incidence 1995–2005 from forty population-based registries. We calculated age-adjusted trends using annual percent change HPV-association. Results Males Non-Hispanic Blacks experienced greater compared women other groupings. A significant overall increase was observed among HPV-associated sites during 1995–2005, while non decline incidence. Overall, younger age groups, Whites Hispanics increases sites, declined independent HPV-association. In particular, White males aged 45–54 increased at greatest rate, an APC 6.28% (p<0.05). Among Black 0–44 years reduction (APC, −8.17%, p<0.05), older, 55–64 year group −5.44%, p<0.05) occurred females. Conclusions This provides evidence that tumors are affecting certain representing different disease process tumors. Our suggests HPV tumor status should be incorporated into treatment decisions patients improve prognosis survival.