Recent advances in the chemistry of 1,3,4-thiadiazoles.

摘要: Publisher Summary This chapter discusses homologs, functional groups, physical properties, and the uses of 1, 3, 4-thiadiazole. The development 5- thiadiazole chemistry is linked to discovery phenylhydrazine hydrazine. numbering 4-thiadiazole ring follows from 1. Clockwise or anticlockwise used according convenience. In 2- 5-imino-, -oxo-, -thiono-1, 4- 4-thiadiazoles, position “extra” hydrogen atom shown by corresponding number in parentheses, e.g., 4-thiadiazolin-2(3)-one(2). Analysis microwave spectra three isotopically substituted species can determine structure molecule with an uncertainty 0.03 A coordinates atoms less than 0.003 other atoms. By analysis differences between measured bond lengths covalent radii, authors came conclusion that aromatic character, as r-electron delocalization, decreases order 2, 5-thiadiazole > thiophene oxadiazole.