Formation, Maintenance and Plasticity of Synapses

摘要: So far, the structure and function of nervous systems adult animals has been considered. Furthermore, very little attention paid to any dynamic functions over long time scales: neuromodulation long-term potentiation are only examples such that have mentioned. Likewise, no consideration given structural changes. But system, like all other systems, develops out a single cell — fertilized egg formation complex system contains so many individual cells whose interconnexions paramount importance for its functioning must surely be controlled by strict set instructions. Also, during course lifetime an animal may exposed numerous threats might lead damage (e.g. poisoning, wounds result in loss limb or parts central infections etc.), question arises as how copes with indeed whether it can cope at all? A related question, even absence externally imposed changes neuronal structure, is: How synaptic connexions, once formed development, maintained rest animal’s life? Is necessary particular connexions used order their integrity maintained? These questions will considered this chapter. Finally, prime is learn remember, would seem remember there perhaps connexions. Chapter 18 address these problems.