Calycosin induces apoptosis in osteosarcoma cell line via ERβ‑mediated PI3K/Akt signaling pathways.
作者： Wei Tian , Zhi‑Wei Wang , Bao‑Ming Yuan , Yong‑Ge Bao
关键词:
摘要: … types of cancer, including breast cancer and renal cell carcinoma (… of ERβ may inhibit tumor development and progression. … that the inhibitory effects of calycosin on OS MG-63 cells are …
sci-hub.st 参考文章(33)
Jin Wang, Chao Zhang, Keming Chen, Hailin Tang, Jun Tang, Cailu Song, Xiaoming Xie, ERβ1 inversely correlates with PTEN/PI3K/AKT pathway and predicts a favorable prognosis in triple-negative breast cancer Breast Cancer Research and Treatment. ,vol. 152, pp. 255- 269 ,(2015) , 10.1007/S10549-015-3467-3
Yingxi Xu, Na Li, Rong Xiang, Peiqing Sun, Emerging roles of the p38 MAPK and PI3K/AKT/mTOR pathways in oncogene-induced senescence Trends in Biochemical Sciences. ,vol. 39, pp. 268- 276 ,(2014) , 10.1016/J.TIBS.2014.04.004
Rubiao Qiu, Gang Ma, Chenguang Zheng, Xiaoxia Qiu, Xinning Li, Xueyu Li, Jianlan Mo, Zhengzhao Li, Yun Liu, Linjian Mo, Guan Bi, Yu Ye, None, Antineoplastic effect of calycosin on osteosarcoma through inducing apoptosis showing in vitro and in vivo investigations Experimental and Molecular Pathology. ,vol. 97, pp. 17- 22 ,(2014) , 10.1016/J.YEXMP.2014.04.014
Sanjeev Gupta, George E.N. Kass, Eva Szegezdi, Bertrand Joseph, The mitochondrial death pathway: a promising therapeutic target in diseases. Journal of Cellular and Molecular Medicine. ,vol. 13, pp. 1004- 1033 ,(2009) , 10.1111/J.1582-4934.2009.00697.X
Jack-Michel Renoir, Estradiol receptors in breast cancer cells: associated co-factors as targets for new therapeutic approaches. Steroids. ,vol. 77, pp. 1249- 1261 ,(2012) , 10.1016/J.STEROIDS.2012.07.019
Paul Thelen, Wolfgang Wuttke, Dana Seidlová-Wuttke, Phytoestrogens selective for the estrogen receptor beta exert anti-androgenic effects in castration resistant prostate cancer The Journal of Steroid Biochemistry and Molecular Biology. ,vol. 139, pp. 290- 293 ,(2014) , 10.1016/J.JSBMB.2013.06.009
Hui Li, Zhenzhen Tu, Lianxiao An, Zhiyu Qian, Samuel Achilefu, Yueqing Gu, Inhibitory effects of ERβ on proliferation, invasion, and tumor formation of MCF-7 breast cancer cells--prognostication for the use of ERβ-selective therapy. Pharmaceutical Biology. ,vol. 50, pp. 839- 849 ,(2012) , 10.3109/13880209.2011.637506
Amanda H. Y. Lin, Rachel W. S. Li, Eva Y. W. Ho, George P. H. Leung, Susan W. S. Leung, Paul M. Vanhoutte, Ricky Y. K. Man, Differential Ligand Binding Affinities of Human Estrogen Receptor-α Isoforms PLoS ONE. ,vol. 8, pp. e63199- ,(2013) , 10.1371/JOURNAL.PONE.0063199
Jian Chen, Ruanling Hou, Xing Zhang, Yu Ye, Yong Wang, Jing Tian, Calycosin suppresses breast cancer cell growth via ERβ-dependent regulation of IGF-1R, p38 MAPK and PI3K/Akt pathways. PLOS ONE. ,vol. 9, ,(2014) , 10.1371/JOURNAL.PONE.0091245
Kyung-A Hwang, Min-Ah Park, Nam-Hee Kang, Bo-Rim Yi, Sang-Hwan Hyun, Eui-Bae Jeung, Kyung-Chul Choi, Anticancer effect of genistein on BG-1 ovarian cancer growth induced by 17 β-estradiol or bisphenol A via the suppression of the crosstalk between estrogen receptor alpha and insulin-like growth factor-1 receptor signaling pathways Toxicology and Applied Pharmacology. ,vol. 272, pp. 637- 646 ,(2013) , 10.1016/J.TAAP.2013.07.027