Association of viral hepatitis A with HLA-A9

作者: B. Arce-Gomez , R.A. Moliterno , A.L. Rodrigues , J. Barbosa , M.R.P. deOliveira

DOI: 10.1016/0198-8859(87)90085-1

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摘要: HLA-A and B phenotyping was carried out, during a viral hepatitis A (VHA) epidemic in Brazil, on 47 unrelated patients with VHA 53 healthy subjects of the same age, sex, social status, ethnic origin. An increased frequency HLA-A9 (44.7% vs. 15.1%) decrease that HLA-A3 (2.1% 22.6%) were observed when compared controls. After correction for number antigens tested, only positive association observed. It found relative risk an carrier to develop 4.5.

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