The Effect of Combined Systemic Erythropoietin and Steroid on Non-arteritic Anterior Ischemic Optic Neuropathy: A Prospective Study.
作者： Mohammad Pakravan , Hamed Esfandiari , Kiana Hassanpour , Sarvnaz Razavi , Parastou Pakravan
DOI: 10.1080/02713683.2016.1270328
关键词:
摘要: ABSTRACTBackground: To investigate the effect of combined intravenous (IV) erythropoietin (EPO) and corticosteroid as well systemic steroid alone for treatment non-arteritic anterior ischemic optic neuropathy (NAION).Methods: In this prospective interventional comparative case series, 113 consecutive patients diagnosed with recent onset (less than 14 days) NAION were included. Patients categorized into three groups. 40 received IV recombinant human (rhEPO) (group 1), 43 2), 30 enrolled control group 3). Functional structural outcomes analyzed 3 6 months after treatment. Best corrected visual acuity (BCVA) was main outcome, mean deviation (MD) peripaillary retinal nerve fiber layer thickness (PRNFLT) secondary outcome measures.Results: The BCVA at time presentation 0.98 (±0.65), 0.96 (±0.67), 1.0...
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