Oxygenation and hemodynamic changes during one-lung ventilation: Effects of CPAP10, PEEP10, and CPAP10/PEEP10

摘要: Abstract The effects of 10 cm H 2 0 positive end-expiratory pressure (PEEP ), continuous airway (CPAP10), and their combination (CPAP /PEEP ) on oxygenation hemodynamics were studied in 20 patients undergoing one-lung ventilation (OLV) with 50% nitrous oxide, isoflurane, oxygen. Compared to OLV alone, CPAP significantly increased Pa0 (from 80 ± 6 125 11 137 17 mmHg, respectively); SaO2 93.9 0.8 97.1 0.5 97.0 0.6%, decreased Q s /Q t % 36.4 1.6 26.2 2.0 23.2 2.0%, respectively). Although not statistically significant, PEEP caused an increase PaO (to 105 12 mmHg) a decrease 27.6 2.1%), which are clinical significance. However, significant cardiac output 4.50 0.26 3.83 0.22 L/min), stroke volume (58.6 3.0 52.8 2.9 mL/beat), oxygen delivery (653 39 590 38 mL/min). Application , or had no effect heart rate, arterial, pulmonary mean capillary wedge central venous pressures, systemic vascular resistances, mixed saturation. Overall, the most beneficial during N O, isoflurane