Interaction energy of model lipid membranes with water and diiodomethane

作者: Emil Chibowski , Malgorzata Jurak

DOI: 10.1016/J.COLSURFA.2011.01.001

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摘要: Abstract The Langmuir–Blodgett/Schaefer (LB/LS) method and contact angle measurements were applied to study interaction energy of lipid films with water diiodomethane. membranes formed on mica constituted single-component saturated phospholipids 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) or unsaturated 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) cholesterol (Chol), they binary systems DPPC/DOPC DPPC/Chol varying DOPC Chol molar ratio. surface free single mono- bilayers was evaluated from the advancing receding angles diiodomethane using hysteresis (CAH) model. Taking into account areas occupied by one molecule in packed monolayers determined π – A isotherms calculated layers, energies mole evaluated. Thus obtained values DPPC agree well some literature data available. It is believed that this procedure evaluation provided a framework for better understanding interactions occurring biological their wettability.

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